Ginecology, Pediatric Diseases & Experimental Surgery
Bioengineering, Cell Therapy & Surgery in Congenital Malformations
Vincenç Martínez Ibáñez
Principal Investigator Jose L. Peiró Ibáñez, Mario Marotta Baleriola | Researchers Carles Giné Pradas, Josep Lloret, Marc Oria Alonso, Andrés Molino Gahete, Ana Laín, Héctor Boix Alonso, Felix Castillo Salinas, Carmen Ribes, Gabriela Guillen Burrieza, Sergio Lopez Fernández | Researchers in training Paola Contreras Muñoz, Marta Massó Estradé
Summary
The Bioengineering, Cell therapy and Surgery in Congenital Malformations multidisciplinary research team has a large expertise in diagnosis and prenatal treatment of congenital malformations, clinical and basic research, advanced surgical techniques, stem cells biology, bioengineering, regenerative medicine and the development of new in vivo models in order to reproduce human pathologies. In the last year we focused our research on developing new animal models which mimic human pathologies and developing innovative therapies based on the use of advanced surgical technologies in combination with regenerative medicine, stem cells-based treatments and nanomedicine. In addition, as a result of pre-clinical research carried out in animal models, our clinical team members have successfully translated the minimally invasive fetoscopic prenatal surgical approach to the human clinics for the repair of Congenital diaphragmatic hernia (CDH) and Myelomeningocele (MMC) defects in human fetuses operated in the Vall d’Hebron University Hospital in Barcelona, being a worldwide pioneer team in the use of fetoscopy for the prenatal repair of human congenital malformations.