Ginecology, Pediatric Diseases & Experimental Surgery
Musculoskeletal Tissue Engineering
Màrius Aguirre Canyadell
Researchers Sergi Barrera Ochoa, Diego Collado Gastalver, Daniel Alejandro Pacha Vicente, Roberto Vélez Villa | Researchers in trainin Marc Aguilar García, Irene Gallardo Calero, Alba López Fernández, Andrea Sallent Font, Anna Server Salvà, Matías Vicente Goma-Camps.
Summary
Our group has been working in the evaluation of bone regeneration therapies in preclinical and clinical studies. We are evaluating mesenchymal stem cells expanded “ex vivo” associated with different scaffolds in ovine experimental models and also in an early phase clinical trial. We are also working in the osteoproductive, revitalizing and osteointegrative capacity of vascularized periosteal flaps in a rat animal model.
During this year we have joined the PARITY trial and received full approval to start patient recruitment. PARITY is the first ever multi-centre, international, prospective randomized trial in the field of orthopedic oncology. This trial will enroll 600 patients and compare the rates of deep infection in endoprosthetic reconstruction of the lower limb between two prophylactic antibiotic durations (24 hours and 5 days).