Neurosciences
Translational Bioinformatics
Xavier de la Cruz Montserrat
Team Casandra Riera, Natàlia Padilla, Elena Álvarez de la Campa, Òscar Marín
Summary
The Translational Bioinformatics group has followed two different directions to maximize the biomedical reach of its research: first, develop a better understanding of the molecular processes underlying disease and its treatment, and second, reinforce the collaborations with biomedical/clinical groups. For the first goal, we have focused our research in the direction of getting more accurate pathogenicity predictors for specific genes, like CADASIL and NF1. For, the second goal we have focused on projects involving large scale sequencing experiments, of which our collaboration with the group of Dr. Seoane (VHIO) is an outstanding example (Mattos-Arruda et al., Nat. Comm., 2015).
We also have been actively involved in training activities, of which I would like to single out our specialised course on exome/panel sequencing. This course was given at the VHIR, in collaboration with the CNAG (February,11th and 18th, 2015), and at Zaragoza, after an invitation by the Instituto De Investigación Sanitaria Aragón (IIS Aragón).